High Incidence of Ischemic Stroke with Alpha-blocker Therapy in Older Patients

High Incidence of Ischemic Stroke with Alpha-blocker Therapy in Older Patients

High Incidence of Ischemic Stroke with Alpha-blocker Therapy in Older Patients Introduction Ischemic stroke occurs as a result of reduced blood supply to the brain. Alpha-blockers also called as alpha-adrenergic-antagonists are the anti-hypertensive agents. Alpha-blockers may cause hypotension and cerebral hypoperfusion during the early start of the therapy. Cerebral hypoperfusion is a condition caused by the decrease in the blood flow...   Read more


Combo of Fimasartan/Hydrochlorothiazide benefits Hypertensive Patients

Combo of Fimasartan/Hydrochlorothiazide benefits Hypertensive Patients Hypertension is a major independent risk factor for coronary artery disease, stroke, and renal failure. Reducing the blood pressure below the target goal is important to prevent cardiovascular and cerebrovascular events. Fimasartan is one of the new antihypertensive drugs that lower the BP by blocking the angiotensin II type 1 receptor. Availability of various antihyper...   Read more


The Combination Of Olmesartan Plus Calcium Channel Blocker Is Superior To Olmesartan Plus Diuretic

The Combination of Olmesartan Plus Calcium Channel Blocker is Superior To Olmesartan Plus Diuretic Background information Hypertension is associated with cardiovascular disease. Long term blood pressure control can be achieved by combination therapies. It is still unclear which combination therapy is safer and beneficial for the prevention of cardiovascular disease. Angiotensin receptor blocker is often combined with a calcium channel blo...   Read more


Spironolactone Reduces Arterial Resistant Hypertension

Spironolactone Reduces Arterial Resistant Hypertension Background Information Resistant hypertension is a clinical problem where the hypertension remains above the goal in spite of using other anti-hypertensive agents. If there is no secondary cause for hypertension, multidrug treatment regimens including 3, 4, or more number of drugs are necessary to lower the blood pressure. Spironolactone, a mineralocorticoid receptor antagonist causes...   Read more


Rosuvastatin Improves Arterial Stiffness and Blood Pressure in Case of Inflammatory Joint Disease

Long-Term Rosuvastatin Treatment Improves Arterial Stiffness and Blood Pressure in Patients with Inflammatory Joint Disease Background Information High blood pressure is a common disease in patients with inflammatory joint disease (IJD). It is related with the presence of subclinical atherosclerosis and arterial stiffness. The augmentation index (Alx) and the aortic pulse wave velocity (Apwv) are the measures of arterial stiffness that pr...   Read more


Ivabradine is More Potent than Metoprolol in Improving Hemodynamic Parameters

Ivabradine is More Potent Than Metoprolol in Improving Hemodynamic Parameters in the Patients with Mild to Moderate Mitral Stenosis Background Information Mitral stenosis is a valvular heart disease which is characterized by the narrowing of the orifice of the mitral valve of the heart. It is studied both at rest and during exercise. Transmitral gradient increase with the heart rate during exercise results in elevated pulmonary venous pressu...   Read more


Drug-Eluting Stents is better than Bare-Metal Stents for Left Main Coronary Artery Disease

Drug-Eluting Stents Better than Bare-Metal Stents for the Treatment of Left Main Coronary Artery Disease Background Information: The left main coronary artery (LMCA) disease is characterized by atherosclerosis in the epicardial coronary arteries. It is often accompanied by a series of complications such as in-stent restenosis for the treatment of percutaneous coronary intervention (PCI). It has been associated with poor prognosis when treate...   Read more


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